![]() ![]() The recommendation to gradually discontinue metoprolol is generally true for all beta-blocker medications, although some are associated with more side effects after abruptly stopping than others. ![]() When discontinuing chronically administered Lopressor, particularly in patients with ischemic heart disease, the dosage should be gradually reduced over a period of 1-2 weeks and the patient should be carefully monitored." Lopressor Package Insert ![]() Per the prescribing information for Lopressor (metoprolol tartrate): "Following abrupt cessation of therapy with certain beta-blocking agents, exacerbations of angina pectoris and, in some cases, myocardial infarction have occurred. Stopping metoprolol abruptly, or 'cold-turkey' can exacerbate chest pains and could potentially increase the risk of heart attack and other symptoms. Metoprolol, a beta-adrenergic antagonist (also known as a 'beta-blocker'), is generally recommended to be tapered (step-wise dose decreases) if you have been taking it chronically. ![]()
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